Scientific Publications - Archive
2007
Binnerts ME, Kim KA, Bright JM, Patel SM, Tran K, Bouchard A, Zhou M, Leung JM, Lomas WE 3rd, Dixon M, Hazell SA, Wagle M., Nie WS, Tomasevic N, Willams J, Zhan X, Levy M, Funk W, Abo A.
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.
Proceedings of the National Academy of Sciences 2007 September 11; 104 (37): 14700-14705.
Giugliano RP, Wiviott SD, Stone PH, Simon DI, Schweiger MJ, Bouchard A, Lessar MA, Goulder MA, Deitcher SR, McCabe CH, Braunwald E.
Journal of American College of Cardiology 2007 June 27; 49 (25): 2398-2407.
Korver W , Singh S, Liu S, Zhao X, Yonkovich S, Sweeney A, Anton K, Lomas W, Greenwood R, Smith A, Hoang-Tran D, Shinkawa P, Jimenez M, Yeung P, Aguilar G, Palencia S, Vatta P, Mueller M, Zhan X, Newton E, Liu Y, Zhao J, Emtage P, Levy MD, Hsi ED, Funk WD, Abo A.
British Journal of Haematology
May 2007, Vol. 137 (4): 307-318.
2006
Deitcher SR, Funk WD, Buchanan J, Liu S, Levy MD, Toombs CF.
Alfimeprase: a novel recombinant direct-acting fibrinolytic
Expert Opinion on Biological Therapy, December 2006, Vol. 6, No. 12, Pages 1361-1369.
Moll S, Kenyon P, Bertoli L, De Maio J, Homesley H, Deitcher S.
Phase II Trial of Alfimeprase, a Novel-Acting Fibrin Degradation Agent, for Occluded Central Venous Access Devices.
J Clin Oncol. 2006 Jul 1;24(19):3056-60.
PMID: 16809729 [PubMed - in process]
Kim KA, Zhao J, Andarmani S, Kakitani M, Oshima T, Binnerts ME, Abo A, Tomizuka K, Funk WD.
R-Spondin Proteins: A Novel Link to beta-catenin Activation.
Cell Cycle. 2006 Jan 8;5(1)
PMID: 16357527
2005
Deitcher, S.
Non-Clinical and Clinical Characterization of a Novel Acting Thrombolytic: Alfimeprase.
Pathophysiol Haemost Thromb. 2005;34:215-220
PMID: 16707931 [PubMed - in process]
Kim KA, Kakitani M, Zhao J, Oshima T, Tang T, Binnerts M, Liu Y, Boyle B, Park E, Emtage P, Funk WD, Tomizuka K.
Mitogenic influence of human R-spondin1 on the intestinal epithelium.
Science. 2005 Aug 19;309(5738):1256-9.
Ouriel K, Cynamon J, Weaver FA, Dardik H, Akers D, Blebea J, Gruneiro L, Toombs CF, Wang-Clow F, Mohler M, Pena L, Wan CY, Deitcher SR.
A phase I trial of alfimeprase for peripheral arterial thrombolysis.
J Vasc Interv Radiol. 2005 Aug;16(8):1075-83.
PMID: 16105919 [PubMed - in process]
Tang YT, Hu T, Arterburn M, Boyle B, Bright JM, Emtage PC, Funk WD.
PAQR Proteins: A Novel Membrane Receptor Family Defined by an Ancient7-Transmembrane Pass Motif.
J Mol Evol. 2005 Jul 21; [Epub ahead of print]
PMID: 16044242 [PubMed - as supplied by publisher]
Tom Tang Y, Hu T, Arterburn M, Boyle B, Bright JM, Palencia S, Emtage PC, Funk WD.
The complete complement of C1q-domain-containing proteins in Homo sapiens.
Genomics. 2005 Jul;86(1):100-11. Epub 2005 Apr 18.
PMID: 15953544 [PubMed - in process]
Cai Z, Chen HT, Boyle B, Rupp F, Funk WD, Dedera DA.
Identification of a novel insulin-like growth factor binding protein gene homologue with tumor suppressor like properties.
Biochem Biophys Res Commun. 2005 May 27;331(1):261-6.
PMID: 15845387 [PubMed - indexed for MEDLINE]
2004
Tom Tang Y, Emtage P, Funk WD, Hu T, Arterburn M, Park EE, Rupp F.
TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain.
Genomics. 2004 Apr;83(4):727-34.
PMID: 15028294 [PubMed - indexed for MEDLINE]
Binnerts ME, Wen X, Cante-Barrett K, Bright J, Chen HT, Asundi V, Sattari P, Tang T, Boyle B, Funk W, Rupp F.
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
Biochem Biophys Res Commun. 2004 Mar 5;315(2):272-80.
PMID: 14766204 [PubMed - indexed for MEDLINE]
2002
Mulero JJ, Boyle BJ, Bradley S, Bright JM, Nelken ST, Ho TT, Mize NK, Childs JD, Ballinger DG, Ford JE, Rupp F.
Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP).
Immunogenetics. 2002 Aug;54(5):293-300. Epub 2002 Jul 2.
PMID: 12185532 [PubMed - indexed for MEDLINE]
2001
Sims JE, Nicklin MJ, Bazan JF, Barton JL, Busfield SJ, Ford JE, Kastelein RA, Kumar S, Lin H, Mulero JJ, Pan J, Pan Y, Smith DE, Young PR.
A new nomenclature for IL-1-family genes.
Trends Immunol. 2001 Oct;22(10):536-7. No abstract available.
PMID: 11574262 [PubMed - indexed for MEDLINE]
Lin H, Ho AS, Haley-Vicente D, Zhang J, Bernal-Fussell J, Pace AM, Hansen D, Schweighofer K, Mize NK, Ford JE.
Cloning and characterization of IL-1HY2, a novel interleukin-1 family member.
J Biol Chem. 2001 Jun 8;276(23):20597-602. Epub 2001 Mar 14.
PMID: 11278614 [PubMed - indexed for MEDLINE]
2000
Yeung G, Mulero JJ, McGowan DW, Bajwa SS, Ford JE.
CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart.
Biochemistry. 2000 Oct 24;39(42):12916-23.
PMID: 11041856 [PubMed - indexed for MEDLINE]
Mulero JJ, Nelken ST, Ford JE.
Organization of the human interleukin-1 receptor antagonist gene IL1HY1.
Immunogenetics. 2000 May;51(6):425-8.
PMID: 10866108 [PubMed - indexed for MEDLINE]
Mulero JJ, Yeung G, Nelken ST, Bright JM, McGowan DW, Ford JE.
Biochemical characterization of CD39L4.
Biochemistry. 2000 Oct 24;39(42):12924-8.
PMID: 11041857 [PubMed - indexed for MEDLINE]
1999
Yeung G, Mulero JJ, Berntsen RP, Loeb DB, Drmanac R, Ford JE.
Cloning of a novel epidermal growth factor repeat containing gene EGFL6: expressed in tumor and fetal tissues.
Genomics. 1999 Dec 1;62(2):304-7.
PMID: 10610727 [PubMed - indexed for MEDLINE]
Mulero JJ, Pace AM, Nelken ST, Loeb DB, Correa TR, Drmanac R, Ford JE.
IL1HY1: A novel interleukin-1 receptor antagonist gene.
Biochem Biophys Res Commun. 1999 Oct 5;263(3):702-6.
PMID: 10512743 [PubMed - indexed for MEDLINE]
Mulero JJ, Yeung G, Nelken ST, Ford JE.
CD39-L4 is a secreted human apyrase, specific for the hydrolysis of nucleoside diphosphates.
J Biol Chem. 1999 Jul 16;274(29):20064-7.
PMID: 10400613 [PubMed - indexed for MEDLINE]